Study Reviews

Paediatric nonalcoholic fatty liver

  • 06/23/2017

The most common chronic liver disease in children and adolescents is nonalcoholic fatty liver disease (NAFLD). Dietary supplementation with omega-3 polyunsaturated fatty acids (PUFAs) represents a promising therapy for paediatric patients...

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Chronic kidney disease-associated pruritus

  • 06/16/2017

Chronic kidney disease-associated pruritus is one of the most frequent and uncomfortable problems in patients with advanced or terminal kidney disease. It affects 15-49% of pre-dialysis patients and 50-90% of those on dialysis (peritoneal...

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Kidney transplantation: levels of omega-3 and inflammation

  • 05/30/2017

With the aim of researching potential anti-inflammatory effects of omega-3 long-chain polyunsaturated fatty acids after kidney transplantation, a cross-sectional study was carried out on 861 patients who had received a kidney transplant at...

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Therapeutic effects of DHA on acute lymphoblastic leukaemia

  • 05/26/2017

Focussing on p53 and survivin expression could represent an attractive therapeutic strategy for acute lymphoblastic leukaemia (ALL), given that resistance to chemotherapy with this disease is associated with p53 inactivation and survivin...

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Erythrocyte EPA, STEMI, infarct size and ventricle function

  • 05/18/2017

Eicosapentaenoic acid (EPA), an omega-3 fatty acid, is easily incorporated into cardiomyocyte membranes, partially displacing arachidonic acid (AA), an omega-6 fatty acid. While AA is a pro-inflammatory eicosanoid precursor, EPA release...

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The effects of EPA and DHA on amyloid-beta protein

  • 05/12/2017

Alzheimer’s disease (AD) is closely linked to excess production and build-up of amyloid-beta peptides as extracellular plaques in the brain. Total amyloid-beta protein levels are not solely dependent on production by lysis of its amyloid...

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Omega-3 is effective in non-alcoholic fatty liver disease

  • 04/28/2017

A recent meta-analysis of randomised, placebo-controlled studies on the efficacy of omega-3 fatty acids in non-alcoholic fatty liver disease (NAFLD) published in PubMed, Cochrane Library and Embase, included 7 studies and a total of 227...

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EPA and statin in the prevention of cardiovascular events

  • 04/19/2017

In patients with acute myocardial infarction (AMI), early combined administration (within the first 24 hours) of eicosapentaenoic acid (EPA) and a statin after a percutaneous coronary intervention reduces inflammation and ventricular...

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Combination of omega-3 and vitamin E in chronic haemodialysis

  • 04/12/2017

A double-blind, randomised, controlled study was carried out on 120 patients to assess the effects of combined supplementation with omega-3 fatty acids (FA) and alpha-tocopherol on the degree of malnutrition-inflammation and the biomarkers...

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DHA can reduce bone resorption

  • 03/23/2017

Docosahexaenoic acid (DHA) has been shown to protect against inflammatory bone disorders such as osteoporosis and rheumatoid arthritis; however, the mechanisms through which it is involved in bone resorption or the molecular mechanisms of...

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