Studies

Sensory organs

Hearing

Vision

Agbaga MG, Merriman DK, Brush RS, Lydic TA, Conley SM, Naash MI, et al. Differential composition of DHA and very long chain PUFAs in rod and cone photoreceptors. J Lipid Res. 2018 Jul 9. doi: 10.1194/jlr.M082495. [Epub ahead of print]


Padmanabha S, Vallikannan B. Fatty acids modulate the efficacy of lutein in cataract prevention: Assessment of oxidative and inflammatory parameters in rats. Biochem Biophys Res Commun. 2018;500(2):435-42.


Downie LE, Gad A, Wong CY, Gray JHV, Zeng W, Jackson DC, et al. Modulating contact lens discomfort with anti-inflammatory approaches: A randomized controlled trial. Invest Ophthalmol Vis Sci. 2018;59(8):3755-66.


Downie LE, Vingrys AJ. Oral Omega-3 Supplementation Lowers Intraocular Pressure in Normotensive Adults. Transl Vis Sci Technol. 2018;7(3):1.


de Paiva CS, Schwartz CE, Gjörstrup P, et al. Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye. Cornea. 2012;31(11):1299-303.


Mendoza RL. Clinical trials with multiple endpoints can establish a correlation, but not (yet) causality, between dietary supplementation with omega-3 fatty acids and keratoconjunctivitis sicca.


Mendoza RL. Clinical trials with multiple endpoints can establish a correlation, but not (yet) causality, between dietary supplementation with omega-3 fatty acids and keratoconjunctivitis sicca. J Med Econ. 2018;21:1-22.


Wang YE, Tseng VL, Yu F, et al. Association of Dietary Fatty Acid Intake With Glaucoma in the United States. JAMA Ophthalmol. 2017 Dec 21. [Epub ahead of print]


Cortina MS, Bazan HE. Docosahexaenoic acid, protectins and dry eye. Curr Opin Clin Nutr Metab Care. 2011;14(2):132-7.


Knott EJ, Gordon WC, Jun B, et al. Retinal Pigment Epithelium and Photoreceptor Preconditioning Protection Requires Docosanoid Signaling. Cell Mol Neurobiol. 2017 Nov 24. [Epub ahead of print]


Gong Y, Fu Z, Liegl R et al. ω-3 and ω-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases. Am J Clin Nutr. 2017 May 17.


Carneiro Â, Andrade JP. Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review.Oxid Med Cell Longev. 2017;2017:6469138. FULL TEXT


Wang L, Chen X, Hao J, Yang L. Proper balance of omega-3 and omega-6 fatty acid supplements with topical cyclosporine attenuated contact lens-related dry eye syndrome. Inflammopharmacology. 2016 Dec;24(6):389-396.


Gong Y, Fu Z, Edin ML, Liu CH, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Lee KS, Moran EP, SanGiovanni JP, Hellström A, Hammock BD, Zeldin DC, Smith LE. Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1919-27. doi: 10.1161/ATVBAHA.116.307558. Epub 2016 Jul 14.


Gorusupudi A, Liu A, Hageman GS et al. Associations of Human Retinal Very Long-chain Polyunsaturated Fatty Acids with Dietary Lipid Biomarkers. J Lipid Res. 2016 Jan 13. pii: jlr.P065540. FULL TEXT


Gorusupudi A, Liu A, Hageman GS et al. Associations of Human Retinal Very Long-chain Polyunsaturated Fatty Acids with Dietary Lipid Biomarkers. J Lipid Res. 2016 Jan 13. pii: jlr.P065540. [Epub ahead of print] FULL TEXT


Wakx A, Dutot M, Massicot F, Mascarelli F, Limb GA, Rat P. Amyloid β Peptide Induces Apoptosis Through P2X7 Cell Death Receptor in Retinal Cells: Modulation by Marine Omega-3 Fatty Acid DHA and EPA. Appl Biochem Biotechnol. 2015 Oct 14.


Ramchani-Ben Othman K, Cercy C, Amri M, Doly M, Ranchon-Cole I. Dietary supplement enriched in antioxidants and omega-3 protects from progressive light-induced retinal degeneration. PLoS One. 2015 Jun 4;10(6):e0128395. FULL TEXT


Bhargava R, Kumar P, Phogat H, Kaur A, Kumar M. Oral omega-3 fatty acids treatment in computer vision syndrome related dry eye. Cont Lens Anterior Eye. 2015 Jun;38(3):206-10.


Bhargava R, Kumar P, Phogat H, Kaur A, Kumar M. Oral omega-3 fatty acids treatment in computer vision syndrome related dry eye. Cont Lens Anterior Eye. 2015 Feb 16. pii: S1367-0484(15)00009-0.


Galbis-Estrada C, Pinazo-Durán MD, Martínez-Castillo S, Morales JM, Monleón D, Zanon-Moreno V. A metabolomic approach to dry eye disorders. The role of oral supplements with antioxidants and omega 3 fatty acids. Mol Vis. 2015; 21: 555-567. FULL TEXT


Feher J, Pinter E, Kovács I, Helyes Z, Kemény A, Markovics A, Plateroti R, Librando A, Cruciani F. Irritable eye syndrome: neuroimmune mechanisms and benefits of selected nutrients. Ocul Surf. 2014 Apr;12(2):134-45.


Merle BM, Benlian P, Puche N, Bassols A, Delcourt C, Souied EH; Nutritional AMD Treatment 2 Study Group. Circulating omega-3 Fatty acids and neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2014 Mar 28;55(3):2010-9.


Harauma A, Saito J, Watanabe Y, Moriguchi T. Potential for daily supplementation of n-3 fatty acids to reverse symptoms of dry eye in mice. Prostaglandins Leukot Essent Fatty Acids. 2014 Jun;90(6):207-13. doi: 10.1016/j.plefa.2014.02.005. Epub 2014 Feb 28.


Pinazo-Durán MD, Gómez-Ulla F, Arias L, Araiz J, Casaroli-Marano R, Gallego-Pinazo R, García-Medina JJ, López-Gálvez MI, Manzanas L, Salas A, Zapata M, Diaz-Llopis M, García-Layana A. Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention? J Ophthalmol. 2014;2014:901686. Epub 2014 Jan 23. FULL TEXT


Dawczynski J, Jentsch S, Schweitzer D et al. Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study. Graefes Arch Clin Exp Ophthalmol. 2013 May 22.


Rasmussen HM, Johnson EJ. Nutrients for the aging eye. Clin Interv Aging. 2013;8:741-8. FULL TEXT


Georgiou T, Neokleous A, Nikolaou D et al. Pilot Study for Treating Dry Age-related Macular Degeneration (AMD) with High-Dose Omega-3 Fatty Acids. PharmaNutrition. Published online ahead of print, doi: 10.1016/j.phanu.2013.10.001


Christen WG, Schaumberg DA, Glynn RJ et al. Dietary ?-3 Fatty Acid and Fish Intake and Incident Age-Related Macular Degeneration in Women. Arch Ophthalmol. 2011;129(7):921-929. FULL TEXT


He J, Bazan HE. Omega-3 fatty acids in dry eye and corneal nerve regeneration after refractive surgery. Prostaglandins Leukot Essent Fatty Acids 2010;82(4-6):319-325. FULL TEXT


Seddon JM, George S, Rosner B. Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. Arch Ophthalmol. 2006 Jul;124(7):995-1001.


Bazan NG. The metabolism of omega-3 polyunsaturated fatty acids in the eye: the possible role of docosahexaenoic acid and docosanoids in retinal physiology and ocular pathology. Prog Clin Biol Res 1989; 313: 95-112.