Studies

Pediatrics

Allergies

Asthma

Neurological development of the fetus and children

Collado MC, Santaella M, Mira-Pascual L, Martínez-Arias E, Khodayar-Pardo P, Ros G, Martínez-Costa C. Longitudinal Study of Cytokine Expression, Lipid Profile and Neuronal Growth Factors in Human Breast Milk from Term and Preterm Deliveries. Nutrients. 2015 Oct 19;7(10):8577-91.


Almeida DM, Jandacek RJ, Weber WA, McNamara RK. Docosahexaenoic acid biostatus is associated with event-related functional connectivity in cortical attention networks of typically developing children. Nutr Neurosci. 2015 Oct 13.


Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nat Genet. 2015 May 25. doi: 10.1038/ng.3311.


Sherry CL, Oliver JS, Marriage BJ. Docosahexaenoic acid supplementation in lactating women increases breast milk and plasma docosahexaenoic acid concentrations and alters infant omega 6:3 fatty acid ratio. Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:63-9. doi: 10.1016/j.plefa.2015.01.005. FULL TEXT


Strickland AD. Prevention of cerebral palsy, autism spectrum disorder, and attention deficit - Hyperactivity disorder. Med Hypotheses. 2014 May;82(5):522-8.


Williams JJ, Mayurasakorn K, Vannucci SJ et al. N-3 fatty acid rich triglyceride emulsions are neuroprotective after cerebral hypoxic-ischemic injury in neonatal mice. PLoS One. 2013;8(2):e56233. doi: 10.1371/journal.pone.0056233. Epub 2013 Feb 20. FULL TEXT


Morse NL. Benefits of docosahexaenoic acid, folic acid, vitamin D and iodine on foetal and infant brain development and function following maternal supplementation during pregnancy and lactation. Nutrients. 2012;4(7):799-840. FULL TEXT


Zhang W, Hu X, Yang W, Gao Y, Chen J. Omega-3 polyunsaturated fatty acid supplementation confers long-term neuroprotection against neonatal hypoxic-ischemic brain injury through anti-inflammatory actions. Stroke. 2010 Oct;41(10):2341-7. FULL TEXT


Gil-Campos M, Dalmau Serra J; Comité de Nutrición de la Asociación Española de Pediatría. [Importance of docosahexaenoic acid (DHA): Functions and recommendations for its ingestion in infants]. An Pediatr (Barc). 2010 Sep;73(3):142.e1-8. Epub 2010 Jun 8. FULL TEXT


Carlson SE. Docosahexaenoic acid supplementation in pregnancy and lactation. Am J Clin Nutr. 2009 Feb;89(2):678S-84S. Epub 2008 Dec 30. FULL TEXT


Carlson SE. Docosahexaenoic acid supplementation in pregnancy and lactation. Am J Clin Nutr. 2009 Feb;89(2):678S-84S. Epub 2008 Dec 30. FULL TEXT


Levant B, Radel JD, Carlson SE. Decreased brain docosahexaenoic acid during development alters dopamine-related behaviors in adult rats that are differentially affected by dietary remediation. Behav Brain Res 2004;152:49-57.


Valenzuela A, Nieto S. Ácido docosahexaenoico (DHA) en el desarrollo fetal y en la nutrición materno-infantil. Rev Med Chile. 2001;129:1203-11. FULL TEXT


Valenzuela A, Nieto S. Ácido docosahexaenoico (DHA) en el desarrollo fetal y en la nutrición materno-infantil. Rev Med Chile. 2001;129:1203-11. FULL TEXT

Premature infants

Sleep

Visual and cognitive development in children

Johnson M, Fransson G, Östlund S, Areskoug B, Gillberg C. Omega 3/6 fatty acids for reading in children: a randomized, double-blind, placebo-controlled trial in 9-year-old mainstream schoolchildren in Sweden. J Child Psychol Psychiatry. 2016 Aug 22. doi: 10.1111/jcpp.12614. [Epub ahead of print]


Fu Z, Lofqvist CA, Shao Z, Sun Y, Joyal JS, Hurst CG, Cui RZ, Evans LP, Tian K, SanGiovanni JP, Chen J, Ley D, Hansen Pupp I, Hellstrom A, Smith LE. Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin. Am J Clin Nutr. 2015 Apr;101(4):879-88. doi: 10.3945/ajcn.114.099291.


Colombo J, Carlson SE, Cheatham CL, Shaddy DJ, Kerling EH, Thodosoff JM, Gustafson KM, Brez C. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013 Aug;98(2):403-12. FULL TEXT


Kuratko CN, Barrett EC, Nelson EB et al. The relationship of docosahexaenoic acid (DHA) with learning and behavior in healthy children: a review. Nutrients. 2013 Jul 19;5(7):2777-2810. FULL TEXT


Lassek WD, Gaulin SJ. Maternal milk DHA content predicts cognitive performance in 28 nations. Matern Child Nutr 2013; Jun 25 doi: 10.1111/mcn.12060


Richardson AJ, Burton JR, Sewell RP et al. Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study). PLoS One 2012;7(9):e43909. FULL TEXT


Jacques C, Levy E, Muckle G et al. Long-term effects of prenatal omega-3 fatty acid intake on visual function in school-age children. J Pediatr 2011;158(1):83-90. FULL TEXT


Birch EE, Carlson SE, Hoffman DR et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr. 2010 Apr;91(4):848-59. FULL TEXT


Heird WC, Lapillonne A. The role of essential fatty acids in development. Annu Rev Nutr. 2005;25:54971.


Uauy R, Hoffman D, Peirano P, Birch D, Birch E. Essential fatty acids in visual and brain development. Lipids. 2001;36:885-95.


Uauy R, Mena P, Valenzuela A. Essential fatty acids as determinants of lipid requirements in infants, children and adults. Eur J Clin Nutr 1999; 53: 66-77


Cunnane S. Fatty acid profiles of maternal adipose tissue in relation to infant development. Brit J Nutr 1999; 82: 253-4.


Birch E, Hoffman D, Uauy R. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res 1998; 44: 1-9.


Agostoni C, Trojan S, Bellú R, Riva E, Brunezze M, Giovannini M. Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow-up study. Arch Dis Child. 1997;76:421-4. FULL TEXT


Agostoni C, Trojan S, Bellú R, Riva E, Brunezze M, Giovannini M. Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow-up study. Arch Dis Child. 1997;76:421-4. FULL TEXT


Sastry P. Lipids in the nervous system: Compo sition and metabolism. Prog Lipid Res. 1985;24:69-176.