Studies

Gynecology

Wang H, Cai Y, Shao Y, Zhang X, Li N, Zhang H, et al. Fish Oil Ameliorates High-Fat Diet Induced Male Mouse Reproductive Dysfunction via Modifying the Rhythmic Expression of Testosterone Synthesis Related Genes. Int J Mol Sci. 2018;19(5).



Kitamura Y, Kogomori C, Hamano H, Maekawa I, Shimizu T5 Shiga S. Fatty Acid Composition of the Erythrocyte Membranes Varies between Early-Term, Full-Term, and Late-Term Infants in Japan. Ann Nutr Metab. 2018;73(4):335-43.


Chen CY, Chen CY, Liu CC, Chen CP. Omega-3 polyunsaturated fatty acids reduce preterm labor by inhibiting trophoblast cathepsin S and inflammasome activation. Clin Sci (Lond). 2018;132(20):2221-39.


Thavamani A, Mhanna MJ, Groh-Wargo S, Gulati R, Shekhawat PS. Enteral fish oil supplementation in the resolution of parenteral nutrition associated cholestasis. J Neonatal Perinatal Med. 2018 Oct 22. doi: 10.3233/NPM-18138. [Epub ahead of print]


Islam MS, Castellucci C, Fiorini R, Greco S, Gagliardi R, Zannotti A, et al. Omega-3 fatty acids modulate the lipid profile, membrane architecture, and gene expression of leiomyoma cells. J Cell Physiol. 2018 Mar 25. [Epub ahead of print]


Mirhashemi SM, Sahmani M, Salehi B, et al. Metabolic Response to Omega-3 Fatty Acids and Vitamin E Co-Supplementation in Patients with Fibrocystic Breast Disease: A Randomized, Double-Blind, Placebo-Controlled Trial. Arch Iran Med. 2017 Aug;20(8):466-73.


Soldo D, Matija MK, Lara SB, Nikolina P, Martina O, Neven S, et al. Effect of n-3 long-chain polyunsaturated fatty acids supplementation in healthy mothers on DHA and EPA profiles in maternal and umbilical blood: a randomized controlled trial. J Perinat Med. 2018 Oct 13. doi: 10.1515/jpm-2018-0155. [Epub ahead of print]


Wise LA, Wesselink AK, Tucker KL, Saklani S, Mikkelsen EM, Cueto H, et al. Dietary fat intake and fecundability in two preconception cohort studies. Am J Epidemiol. 2017 Jun 8. [Epub ahead of print]

Breastfeeding

Bruun S, van Rossem L, Lauritzen L, Husby S, Neergaard Jacobsen L, Michaelsen KF, Boysen Sandberg M, Stark KD, Sørensen J, Zachariassen G. Content of n-3 LC-PUFA in Breast Milk Four Months Postpartum is Associated with Infancy Blood Pressure in Boys and Infancy Blood Lipid Profile in Girls. Nutrients. 2019 Jan 22;11(2). pii: E235. doi: 10.3390/nu11020235.


Argaw A, Huybregts L, Wondafrash M, Kolsteren P, Belachew T, Worku BN, Abessa TG, Bouckaert KP. Neither n-3 Long-Chain PUFA Supplementation of Mothers through Lactation nor of Offspring in a Complementary Food Affects Child Overall or Social-Emotional Development: A 2 × 2 Factorial Randomized Controlled Trial in Rural Ethiopia. J Nutr. 2018 Dec 12. doi: 10.1093/jn/nxy202. [Epub ahead of print]


Rodriguez-Santana Y, Ochoa JJ, Lara-Villoslada F, et al. Cytokine distribution in mothers and breastfed children after omega-3 LCPUFAs supplementation during the last trimester of pregnancy and the lactation period: A randomized, controlled trial. Prostaglandins Leukot Essent Fatty Acids. 2017;126:32-8.


Weiss GA, Troxler H, Klinke G, Rogler D, Braegger C, Hersberger M, High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation. 2013 June 15 FULL TEXT


Juber BA, Jackson KH, Johnson KB, Harris WS, Baack ML. Breast milk DHA levels may increase after informing women: a community-based cohort study from South Dakota USA. Int Breastfeed J. 2017 Jan 28;12:7. doi: 10.1186/s13006-016-0099-0. eCollection 2016. FULL TEXT


Panagos PG, Vishwanathan R, Penfield-Cyr A et al. Breastmilk from obese mothers has pro-inflammatory properties and decreased neuroprotective factors. J Perinatol. 2016 Jan 7. doi: 10.1038/jp.2015.199. [Epub ahead of print] FULL TEXT

Dysmenorrhoea

Endometriosis

Menopause

Gomes MA, Jia X, Kolenski I, Duncan AM, Meckling KA. The role of background diet on the effects of eicosapentaenoic acid and docosahexaenoic acid supplementation in healthy pre-menopausal women: a randomized, cross-over, controlled study. Lipids Health Dis. 2016 Sep 29;15(1):168. FULL TEXT


Losurdo P, Grillo A, Panizon E, Zanetti M, Bardelli M, Biolo G, Fabris B, Carretta R. Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause. Vascul Pharmacol. 2015 Aug;71:65-9.


Graversen CB, Lundbye-Christensen S, Thomsen B, Christense JH, Schmidt EB. Marine n-3 polyunsaturated fatty acids lower plasma proprotein convertase subtilisin kexin type 9 levels in pre- and postmenopausal women: A randomised study. Vascul Pharmacol. 2015 Jul 2. pii: S1537-1891(15)00149-4.


Losurdo P, Grillo A, Panizon E, Zanetti M, Bardelli M, Biolo G, Fabris B, Carretta R. Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause. Vascul Pharmacol. 2015 Apr 8. pii: S1537-1891(15)00038-5. doi: 10.1016/j.vph.2014.12.005.


Ramsden CE, Faurot KR, Zamora D et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: A randomized trial. Pain. 2013 Jul 22. pii: S0304-3959(13)00396-5. FULL TEXT


Tartibian B, Maleki BH, Kanaley et al. Long-term aerobic exercise and omega-3 supplementation modulate osteoporosis through inflammatory mechanisms in post-menopausal women: a randomized, repeated measures study. Nutrition & Metabolism 2011;8:71. FULL TEXT


Freeman MP, Hibbeln JR, Silver M et al. Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trial. Menopause 2011;18(3):279-284. FULL TEXT


Lucas M, Asselin G, Mérette C, Poulin MJ, Dodin S. Effects of ethyl-eicosapentaenoic acid omega-3 fatty acid supplementation on hot flashes and quality of life among middle-aged women: A double-blind, placebo-controlled, randomized clinical trial. Menopause 2009;16(2):357-66.


Monterrosa A. ¿Qué hacer en la atención primaria de la mujer en menopausia y climaterio? Med UNAB. 2005;8:137-46. FULL TEXT

Perinatal depression

US Preventive Services Task Force, Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW Jr, Grossman DC, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB. Interventions to Prevent Perinatal Depression: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Feb 12;321(6):580-587.


Wei-Hong L, Cheng-Gui Z, Peng-Fei G, Heng L, Jian-Fang Y. Omega-3 Fatty acids as Monotherapy in Treating Depression in Pregnant Women: a Meta- Analysis of Randomized Controlled Trials. Iran J Pharm Res. 2017;16(4):1593-99.


Rechenberg K, Humphries D. Nutritional interventions in depression and Perinatal depression. Yale J Biol Med 2013;86(2):127-137. FULL TEXT


Levant B. N-3 (Omega-3) Fatty Acids in Postpartum Depression: Implications for Prevention and Treatment. Depress Res Treat 2011; 2011: 467349 (16 pp.). FULL TEXT


Alexis Tapia S. Ácidos grasos omega 3 para la prevención y tratamiento de las depresiones en el embarazo y postparto. Rev Chil Obstet Ginecol. 2004;69(5):399-403. FULL TEXT


Otto SJ, de Groot RH, Hornstra G. Increased risk of postpartum depressive symptoms is associated with slower normalization after pregnancy of the functional docosahexaenoic acid status. Prostaglandins Leukot Essent Fatty Acids 2003; 69(4): 237-43.


Chiu CC, Huang SY, Shen WW, Su KP. Omega-3 fatty acids for depression in pregnancy. Am J Psychiatry 2003; 160(2): 385. FULL TEXT


De Vriese SR, Christophe AB, Maes M. Lowered serum n-3 polyunsaturated fatty acid (PUFA) levels predict the occurrence of postpartum depression: Further evidence that lowered n-PUFAs are related to major depression. Life Sci 2003; 73 (25) 3181-7.


Holman RT, Johnson SB, Ogburn PL. Deficiency of essential fatty acids and membrane fluidity during pregnancy and lactation. Proc Natl Acad Sci USA 1991; 88(11): 4835-9. FULL TEXT

Polycystic ovary syndrome

Preeclampsia

Pregnancy

Nandi A, Wadhwani N, Joshi SR.Vitamin D deficiency influences fatty acid metabolism. Prostaglandins Leukot Essent Fatty Acids. 2019 Jan;140:57-63.


Hoge A, Bernardy F, Donneau AF, Dardenne N, Degée S, Nisolle M, Guillaume M, Castronovo V.Importance of n-3 PUFA consumption during pregnancy: perception discrepancies between pregnant women and gynaecologists-obstetricians in Belgium. Public Health Nutr. 2019 Feb 20:1-10.


Thompson M, Hein N, Hanson C, Smith LM, Anderson-Berry A, Richter CK, Stessy Bisselou K, Kusi Appiah A, Kris-Etherton P, Skulas-Ray AC, Nordgren TM. Omega-3 Fatty Acid Intake by Age, Gender, and Pregnancy Status in the United States: National Health and Nutrition Examination Survey 2003⁻2014.Nutrients. 2019 Jan 15;11(1).


Nordgren TM, Anderson Berry A, Van Ormer M, Zoucha S, Elliott E, Johnson R, McGinn E, Cave C, Rilett K, Weishaar K, Maddipati SS, Appeah H, Hanson C. Omega-3 Fatty Acid Supplementation, Pro-Resolving Mediators, and Clinical Outcomes in Maternal-Infant Pairs. Nutrients. 2019 Jan 5;11(1). pii: E98. doi: 10.3390/nu11010098.


Thompson M, Hein N, Hanson C, Smith LM, Anderson-Berry A, Richter CK, Stessy Bisselou K, Kusi Appiah A, Kris-Etherton P, Skulas-Ray AC, Nordgren TM. Omega-3 Fatty Acid Intake by Age, Gender, and Pregnancy Status in the United States: National Health and Nutrition Examination Survey 2003⁻2014. Nutrients. 2019 Jan 15;11(1). pii: E177. doi: 10.3390/nu11010177.


Baroni L, Goggi S, Battaglino R, Berveglieri M, Fasan I, Filippin D, Griffith P, Rizzo G, Tomasini C, Tosatti MA, Battino MA. Vegan Nutrition for Mothers and Children: Practical Tools for Healthcare Providers. Nutrients. 2018 Dec 20;11(1). pii: E5. doi: 10.3390/nu11010005.


León-Aguilar LF, Croyal M, Ferchaud-Roucher V, Huang F, Marchat LA, Barraza-Villarreal A, Romieu I, Ramakrishnan U, Krempf M, Ouguerram K, Mercado-Camargo R, Bolaños-Jiménez F. Maternal obesity leads to long-term altered levels of plasma ceramides in the offspring as revealed by a longitudinal lipidomic study in children. Int J Obes (Lond). 2018 Dec 19. doi: 10.1038/s41366-018-0291-y. [Epub ahead of print]


Huang J, Xue M, Zhang J, Yu H, Gu Y, Du M, Ye W, Wan B, Jin M, Zhang Y. Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism. EBioMedicine. 2019 Jan;39:540-551. doi: 10.1016/j.ebiom.2018.12.019. Epub 2018 Dec 18.


Vahdaninia M, Mackenzie H, Dean T, Helps S. ω-3 LCPUFA supplementation during pregnancy and risk of allergic outcomes or sensitization in offspring: A systematic review and meta-analysis. Ann Allergy Asthma Immunol. 2018 Dec 12. pii: S1081-1206(18)31528-X. doi: 10.1016/j.anai.2018.12.008. [Epub ahead of print]


Jackson KH, Harris WS. A Prenatal DHA Test to Help Identify Women at Increased Risk for Early Preterm Birth: A Proposal. Nutrients. 2018 Dec 6;10(12). pii: E1933. doi: 10.3390/nu10121933.


Monthé-Drèze C, Penfield-Cyr A, Smid MC3, Sen S. Maternal Pre-Pregnancy Obesity Attenuates Response to Omega-3 Fatty Acids Supplementation During Pregnancy. Nutrients. 2018 Dec 4;10(12). pii: E1908. doi: 10.3390/nu10121908.


Phang M, Skilton MR. Marine Omega-3 Fatty Acids, Complications of Pregnancy and Maternal Risk Factors for Offspring Cardio-Metabolic Disease. Mar Drugs. 2018;16(5).


Elliott E, Hanson CK, Anderson-Berry AL, et al. The role of specialized pro-resolving mediators in maternal-fetal health. Prostaglandins Leukot Essent Fatty Acids. 2017;126:98-104.


Gaitán AV, Drewery ML, Thaxton CA, et al. Dietary Intake and Omega-3 DHA Status in Pregnant Women Who Are Overweight. J Obstet Gynecol Neonatal Nurs. 2017 Oct 14.


Büyükuslu N, Ovalı S, Altuntaş ŞL, et al. Supplementation of docosahexaenoic acid (DHA) / Eicosapentaenoic acid (EPA) in a ratio of 1/1.3 during the last trimester of pregnancy results in EPA accumulation in cord blood. Prostaglandins Leukot Essent Fatty Acids. 2017 Oct;125:32-36.


Wadhwani N, Patil V, Joshi S. Maternal long chain polyunsaturated fatty acid status and pregnancy complications. Prostaglandins Leukot Essent Fatty Acids. 2017 Aug 15.


Li GL, Chen HJ, Zhang WX, et al. Effects of maternal omega-3 fatty acids supplementation during pregnancy/lactation on body composition of the offspring: A systematic review and meta-analysis. Clin Nutr. 2017 Aug 10.


Judge MP. Omega-3 Consumption During Pregnancy to Support Optimal Outcomes. J Obstet Gynecol Neonatal Nurs. 2017 Jul 19. [Epub ahead of print]


Bisgaard H, Stokholm J, Chawes BL, Vissing NH, Bjarnadóttir E, Schoos AM, Wolsk HM, Pedersen TM, Vinding RK, Thorsteinsdóttir S, Følsgaard NV, Fink NR, Thorsen J, Pedersen AG, Waage J, Rasmussen MA, Stark KD, Olsen SF, Bønnelykke K. Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring. N Engl J Med. 2016 Dec 29;375(26):2530-9. doi: 10.1056/NEJMoa1503734.


Maddipati KR, Romero R, Chaiworapongsa T, Chaemsaithong P, Zhou S, Xu Z, Tarca AL, Kusanovic JP, Gomez R, Docheva N, Honn KV. Clinical Chorioamnionitis at Term: The Amniotic Fluid Fatty acyl Lipidome. J Lipid Res. 2016 Aug 18. pii: jlr.P069096. [Epub ahead of print] FULL TEXT


Mozurkewich EL, Greenwood M, Clinton C, Berman D, Romero V, Djuric Z, Qualls C, Gronert K. Pathway Markers for Pro-resolving Lipid Mediators in Maternal and Umbilical Cord Blood: A Secondary Analysis of the Mothers, Omega-3, and Mental Health Study. Front Pharmacol. 2016 Sep 7;7:274. doi: 10.3389/fphar.2016.00274. eCollection 2016. FULL TEXT


Ismail AM, Ramadan MF, Ali MK, Abbas AM, El Saman AM, Makarem MH. A randomized controlled study of the efficacy of 4 weeks of supplementation with ω-3 polyunsaturated fatty acids in cases of unexplained oligohydramnios. J Perinatol. 2016 Aug 25. doi: 10.1038/jp.2016.134. [Epub ahead of print]


O'Tierney-Ginn PF, Gillingham M, Fowler J, Brass E, Marshall NE, Thornburg KL. Maternal Weight Gain Regulates Omega-3 Fatty Acids in Male, Not Female, Neonates: A Cross-Sectional Study. Reprod Sci. 2016 Jul 28. pii: 1933719116660843. [Epub ahead of print]


Drewery ML, Gaitán AV, Thaxton C, Xu W, Lammi-Keefe CJ. Pregnant Women in Louisiana Are Not Meeting Dietary Seafood Recommendations. J Pregnancy. 2016;2016:1853935. doi: 10.1155/2016/1853935. Epub 2016 Jul 18. FULL TEXT


Kajarabille N, Hurtado JA, Peña-Quintana L et al. Omega-3 LCPUFA supplement: a nutritional strategy to prevent maternal and neonatal oxidative stress. Matern Child Nutr. 2016 Apr 13. doi: 10.1111/mcn.12300. [Epub ahead of print]


Calabuig-Navarro V, Puchowicz M, Glazebrook P et al. Effect of ω-3 supplementation on placental lipid metabolism in overweight and obese women. Am J Clin Nutr. 2016 Mar 9. pii: ajcn124651. [Epub ahead of print]


Christian LM, Blair LM, Porter K et al. Polyunsaturated Fatty Acid (PUFA) Status in Pregnant Women: Associations with Sleep Quality, Inflammation, and Length of Gestation. PLoS One. 2016 Feb 9;11(2):e0148752. doi: 10.1371/journal.pone.0148752. eCollection 2016. FULL TEXT


Escamilla-Nuñez MC, Barraza-Villarreal A, Hernández-Cadena L, Navarro-Olivos E, Sly PD, Romieu I. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in Children. Chest. 2014 Mar 13. doi: 10.1378/chest.13-1432.


Nishimura RY, Barbieiri P, de Castro GS, Jordão AA Jr, da Silva Castro Perdoná G, Sartorelli DS. Dietary polyunsaturated fatty acid intake during late pregnancy affects fatty acid composition of mature breast milk. Nutrition. 2013 Nov 19. pii: S0899-9007(13)00504-2.


Carlson SE, Colombo J, Gajewski BJ et al. DHA supplementation and pregnancy outcomes. Am J Clin Nutr. 2013;97(4):808-815. FULL TEXT


Larqué E, Gil-Sánchez A, Prieto-Sánchez MT et al. Omega 3 fatty acids, gestation and pregnancy outcomes. Br J Nutr. 2012;107 Suppl 2:S77-S84. FULL TEXT


Hageman JHJ,Hooyenga P, Diersen-Schade DA et al. The Impact of Dietary Long-Chain Polyunsaturated Fatty Acids on Respiratory Illness in Infants and Children. Curr Allergy Asthma Rep 2012;12(6):564-573. FULL TEXT


Contreras M. A, Herrera Y, Rodríguez O. L et al. Aceptabilidad y consumo de una bebida láctea con Omega¬3 en embarazadas y nodrizas del programa nacional de alimentación complementaria. Rev Chil Nutr 2011;38(3): 313¬320. FULL TEXT


Jordan RG. Prenatal omega-3 fatty acids: review and recommendations. J Midwifery Womens Health. 2010;55(6):520-528.


Coletta JM, Bell SJ, Roman AS. Omega-3 fatty acids and pregnancy. Reviews In Obstetrics & Gynecology. 2010;3(4):163-171. FULL TEXT


Van Goor SA, Dijck-Brouwer DA, Hadders-Algra M et al. Human milk arachidonic acid and docosahexaenoic acid contents increase following supplementation during pregnancy and lactation. Prostaglandins Leukot Essent Fatty Acids. 2009;80:65-69.


Koletzko B, Lien E, Agostoni C, Böhles H, Campoy C, Cetin I, y cols. World Association of Perinatal Medicine Dietary Guidelines Working Group. Recommendations and guidelines for perinatal practice. The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: Review of current knowledge and consensus recommendations. J Perinat Med 2008;36:5-14.


Al MD, van Houwelingen AC, Kester AD, Hasaart TH, de Jong AE, Hornstra G. Maternal essential fatty acid patterns during normal pregnancy and their relationship to the neonatal essential fatty acid status. Br J Nutr 1995; 74(1): 55-68.

Prevention of preterm birth