Studies

Dermatology

Sarfaraz Alam M, Ali MS, Zakir F, Alam N, Intakhab Alam M, Ahmad F, Siddiqui MR, Ali MD, Ansari MS, Ahmad S, Ali M. Enhancement of Anti-Dermatitis Potential of Clobetasol Propionate by DHA [Docosahexaenoic Acid] Rich Algal Oil Nanoemulsion Gel. Iran J Pharm Res. 2016 Winter;15(1):35-52. FULL TEXT


Yoshida S, Yasutomo K, Watanabe T. Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. J Med Invest. 2016;63(3-4):187-91. doi: 10.2152/jmi.63.187. FULL TEXT


Barcelos RC, de Mello-Sampayo C, Antoniazzi CT, Segat HJ, Silva H, Veit JC, Piccolo J, Emanuelli T, Bürger ME, Silva-Lima B, Rodrigues LM. Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model. J Dermatol Sci. 2015 Sep;79(3):298-304.


Barcelos RC, de Mello-Sampayo C, Antoniazzi CT, Segat HJ, Silva H, Veit JC, Piccolo J, Emanuelli T, Bürger ME, Silva-Lima B, Rodrigues LM. Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model. J Dermatol Sci. 2015 Sep;79(3):298-304.


Haitz KA, Anandasabapathy N. Docosahexaenoic Acid alleviates atopic dermatitis in mice by generating T regulatory cells and m2 macrophages. J Invest Dermatol. 2015 Jun;135(6):1472-4.


Gruber F, Ornelas CM, Karner S, Narzt MS, Nagelreiter IM, Gschwandtner M, Bochkov V, Tschachler E. Nrf2 deficiency causes lipid oxidation, inflammation and matrix-protease expression in DHA supplemented and UVA irradiated skin fibroblasts. Free Radic Biol Med. 2015 May 13. pii: S0891-5849(15)00217-8. doi: 10.1016/j.freeradbiomed.2015.05.006.


Kendall AC, Pilkington SM, Massey KA, Sassano G, Rhodes LE, Nicolaou A.“Distribution of Bioactive Lipid Mediators in Human Skin.”J Invest Dermatol. 2015 Feb 10. doi: 10.1038/jid.2015.41.


McCusker MM, Grant-Kels JM. Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. Clin Dermatol. 2010 Jul-Aug;28(4):440-51.


Kim HH, Cho S, Lee S, Kim KH, Cho KH, Eun HC, Chung JH. Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo. J Lipid Res. 2006 May;47(5):921-30. Epub 2006 Feb 7. FULL TEXT


Shahbakhti H, Watson RE, Azurdia RM, Ferreira CZ, Garmyn M, Rhodes LE. Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 in human skin in vivo. Photochem Photobiol. 2004 Sep-Oct;80(2):231-5.


Ziboh VA, Miller CC, Cho Y. Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr. 2000 Jan;71(1 Suppl):361S-6S. FULL TEXT


Okuda Y, Sawada T, Mizutani M, Sone H, Suzuki S, Kawakami Y, Soma M, Suzuki M, Yaoita H, Yamashita K. Restoration of myo-inositol uptake by eicosapentaenoic acid in human skin fibroblasts cultured in high-glucose medium. Life Sci. 1995;57(5):PL71-4.


Brown ER, Subbaiah PV. Differential effects of eicosapentaenoic acid and docosahexaenoic acid on human skin fibroblasts. Lipids. 1994 Dec;29(12):825-9.


Grønn M, Christensen E, Hagve TA, Christophersen BO. The Zellweger syndrome: deficient conversion of docosahexaenoic acid (22:6(n-3)) to eicosapentaenoic acid (20:5(n-3)) and normal delta 4-desaturase activity in cultured skin fibroblasts. Biochim Biophys Acta. 1990 May 22;1044(2):249-54.


Rosenthal MD, Whitehurst MC. Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. J Cell Physiol. 1982 Nov;113(2):298-306.